Nicotinamide mononucleotide (NMN) is commonly viewed as an efficient precursor to NAD+, but Nicotinamide riboside (NR), featured in our longevity product Elevate, is drawing significant attention as an contender that could probably be even better. Let us tell you why. 

Takeaways from this article

Role of NMN and NR

NMN and NR are vital precursors to NAD+, essential for maintaining cellular metabolism, DNA health, and other metabolic functions.

Structural Differences

NMN and NR have distinct structures, which can influence their cellular uptake and conversion to NAD+. Research indicates that different tissues may preferentially utilize either NMN or NR.

Clinical Evidence

Both NMN and NR have been tested in human clinical trials, demonstrating their effectiveness in increasing NAD+ levels and confirming their safety for consumption.

Aging and NAD+ Levels

Supplementing with NMN or NR can help counteract the natural decline in NAD+ levels associated with aging, thereby supporting healthy aging.

For various reasons, our NAD levels decrease as we age, significantly impacting our functional and physical aging.

The latest additions to the B3 vitamin family, NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside), show promise as effective NAD supplements. This development is giving researchers worldwide hope for new treatments for age-related diseases and promoting healthier aging*.

So what should I choose - NMN or NR?

When deciding between the latest NAD precursors (NMN and NR), we would recommend NR, as it is approved as a dietary supplement in EU. Some prominent researchers, like Dr. David Sinclair from Harvard, theoretically suggest that NMN supplementation might offer unique benefits not found with NR.

Nevertheless, NR has been the subject of numerous studies since it was the first precursor introduced. It is therefore more heavily backed by research. And the fact that is approved as dietary supplement makes it a safe choice. 

What is Nicotinamide Riboside (NR)?

Nicotinamide Riboside (NR), a more recent B3 derivative, has shown promise in increasing NAD+ levels in the body more effectively than both Niacin and NAM. This is because NR is metabolically closer to NAD, offering several potential benefits.

As a result, nicotinamide riboside is currently subject in scientific research throughout the world, for its possible role in enhancing mitochondrial function, providing anti-aging effects, and benefiting metabolic health. Extensive evaluation in various research models and clinical trials has deemed nicotinamide riboside safe, with no serious side effects reported.

In January 2020, nicotinamide riboside received approval as a dietary supplement in the EU, with a recommended maximum daily intake of 300 mg for adults.

The new anti aging trend - use a NAD+ precursor

Although NR and NMN are present in trace amounts in various foods, consuming enough to significantly elevate NAD+ levels is impractical. Therefore, taking an NAD+ precursor supplement can help counteract the decline. Research in both humans and animals supports the various health benefits of NR.

How can you apply this knowledge today? 

Today, science has shown that NAD precursors such as NR can increase NAD+ levels, and that higher NAD+ levels are associated with healthier aging. Our product, Bevivo Elevate, contains a unique formula with NR along with key ingredients all added for cellular nutrition.